On the Focusrite web pages (at this link) there is a very interesting and complete series of articles under the name of System Science, focusing on audio interfaces. These articles are a must to read if you work or have fun with digital audio, as they fully explain the tools and their features, and it is a precise and in-depth work that will help choosing the right interface for your studio.
The first article focuses on connectors: which one is the right one for your needs? USB3, USB-C, Thunderbolt, Gigabit Ethernet… you will find your way through such an an intricate world of standards. A comprehensive explanation on how data is tranferred by different types of connectors, latency issues, PCI’s, half duplex and full-duplex. Enjoy the full article at focusrite.com